Becca Carlson headshot
My research will help better understand how to design siRNAs with few off-target effects and higher silencing efficacy, saving valuable time and money in aiding in investigation of practically any disease that has a genetic basis.

Chemical Engineering

Research Topic: Designing RNA Molecules to Effectively Silence Genes Graduation Year: 2016

Rebecca Carlson is studying how small interfering RNAs (siRNAs), double-stranded RNA molecules, can be engineered to silence genes more effectively. These molecules silence specific genes by binding to complementary messenger RNA transcripts. In the lab, Carlson is working on determing what factors influence this selection and how that knowledge can be leveraged to design siRNAs wtih strand selection biased toward the more desirable strand. "My research will help better understand how to design siRNAs with few off-target effects and higher silencing efficacy, saving valuable time and money in aiding in investigation of practically any disease that has a genetic basis." 

Click here to read Rebecca's blog post about "Making the Best of a Summer Research Experience"