If you are interested in research even by as little as 1% interest, there is no harm in trying as you can’t know if you really like it until you try it
Oluwabusola Ajagbe
Neuroscience
Undergraduate Research in the Neighborhoods
Chronic pain is reported to affect at least 10% of the world’s population and about 50.2 million Americans daily; and it is reported to be more prevalent in females than males. Oluwabusola hypothesized that the immune response associated with pain, specifically the expression of IL-1B, will be different between male and female mice. To test this hypothesis, she induced inflammatory pain in adult female and male mice by injecting complete Freund’s adjuvant (CFA) into the pain. CFA is known to induce inflammation and pain; pain sensitivity was measured by von Frey filaments and expression of IL-1B was assessed by qPCR from skin samples. Results include that inflammation resolved faster in male than female mice. Identifying the difference in the sensitivity of pain in males and females may provide ways to further identify how to develop sex-specific treatments and help combat pain more effectively.
Learn more about this and other research in the Neighborhood Engagement Centers
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